Persona Q is a crossover video game, containing characters from both Persona 3 and Persona 4 in a game based on Etrian Odyssey, with its perspective, play-style, and systems.

Persona Q's gameplay focuses further on being a dungeon crawler. Players choose to play from the perspective of either the Persona 3 protagonist or the Persona 4 protagonist, with each side featuring slight differences in the main story. The player's choices will also alter the flow of the game.